G-quadruplex-mediated specific recognition, stabilization and transcriptional repression of bcl-2 by small molecule.

Pandya, Nirali; Singh, Mamta; Rani, Reshma; Kumar, Vinit; Kumar, Amit

Pandya, Nirali; Singh, Mamta; Rani, Reshma; Kumar, Vinit; Kumar, Amit.

Afiliação

Pandya N; Department of Biosciences and Biomedical Engineering, Indian Institute of Technology Indore, Simrol, Indore, Madhya Pradesh, 453552, India.
Singh M; Amity Institute of Biotechnology, Amity University Noida, Uttar Pradesh, 201303, India.
Rani R; Amity Institute of Molecular Medicine and Stem Cell Research, Amity University Noida, Uttar Pradesh, 201303, India.
Kumar V; Amity Institute of Biotechnology, Amity University Noida, Uttar Pradesh, 201303, India.
Kumar A; Department of Biosciences and Biomedical Engineering, Indian Institute of Technology Indore, Simrol, Indore, Madhya Pradesh, 453552, India. Electronic address: amitk@iiti.ac.in.

Arch Biochem Biophys ; 734: 109483, 2023 01 15.

Article em En | MEDLINE | ID: mdl-36513132

Assuntos

Quadruplex G; Humanos; Células HeLa; Oncogenes; DNA/metabolismo; Expressão Gênica; Ligantes

Palavras-chave

Apoptosis; Bcl-2 DNA; Cancer; G-quadruplex DNA; Small molecule

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quadruplex G Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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