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Innate Immunity and SARS-CoV-2 Vaccine Response in Hemodialysis Patients.
Valentini, Nicolas; Marchitto, Lorie; Raymond, Maxime; Goyette, Guillaume; Kaufmann, Daniel E; Finzi, Andrés; Suri, Rita S; Lamarche, Caroline.
Afiliação
  • Valentini N; Hôpital Maisonneuve-Rosemont Research Institute, Montreal, Quebec, Canada.
  • Marchitto L; Department of Pharmacology and Physiology, University of Montreal, Montreal, Quebec, Canada.
  • Raymond M; Centre Hospitalier Universitaire de Montreal (CHUM) Research Institute, Montreal, Quebec, Canada.
  • Goyette G; Department of Microbiology, Infectiology and Immunology, University of Montreal, Montreal, Quebec, Canada.
  • Kaufmann DE; Hôpital Maisonneuve-Rosemont Research Institute, Montreal, Quebec, Canada.
  • Finzi A; Centre Hospitalier Universitaire de Montreal (CHUM) Research Institute, Montreal, Quebec, Canada.
  • Suri RS; Centre Hospitalier Universitaire de Montreal (CHUM) Research Institute, Montreal, Quebec, Canada.
  • Lamarche C; Departement of Medicine, University of Montreal, Montreal, Quebec, Canada.
Kidney360 ; 3(10): 1763-1768, 2022 10 27.
Article em En | MEDLINE | ID: mdl-36514720
Patients receiving hemodialysis (HD) have more inflammatory monocytes and less plasmacytoid dendritic cells (DCs) compared with healthy controls.Patients on HD who have a poor antibody response to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine had fewer monocyte-derived DCs and conventional DCs compared with good responders.The defects in antigen presentation might be possible therapeutic targets to increase vaccine efficacy in HD patients.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacinas contra COVID-19 / COVID-19 Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacinas contra COVID-19 / COVID-19 Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article