Tet2- and Tet3- Mediated Cytosine Hydroxymethylation in Six2 Progenitor Cells in Mice Is Critical for Nephron Progenitor Differentiation and Nephron Endowment.

Liang, Xiujie; Aranyi, Tamas; Zhou, Jianfu; Guan, Yuting; Hu, Hailong; Liu, Hongbo; Susztak, Katalin

Liang, Xiujie; Aranyi, Tamas; Zhou, Jianfu; Guan, Yuting; Hu, Hailong; Liu, Hongbo; Susztak, Katalin.

Afiliação

Liang X; Renal, Electrolyte, and Hypertension Division, Department of Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania.
Aranyi T; Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania.
Zhou J; Renal, Electrolyte, and Hypertension Division, Department of Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania.
Guan Y; Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania.
Hu H; Department of Enzymology, Research Centre for Natural Sciences, Budapest, Hungary.
Liu H; Department of Molecular Biology, Semmelweis University, Budapest, Hungary.
Susztak K; Renal, Electrolyte, and Hypertension Division, Department of Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania.

J Am Soc Nephrol ; 34(4): 572-589, 2023 04 01.

Article em En | MEDLINE | ID: mdl-36522157

Assuntos

Dioxigenases; Morte Perinatal; Insuficiência Renal; Gravidez; Feminino; Camundongos; Humanos; Animais; Citosina/metabolismo; Dioxigenases/metabolismo; Néfrons/metabolismo; Diferenciação Celular/genética; Células-Tronco/fisiologia; Metilação de DNA; Insuficiência Renal/genética; Oxigenases de Função Mista/metabolismo; Proteínas Proto-Oncogênicas/genética; Proteínas Proto-Oncogênicas/metabolismo; Proteínas do Tecido Nervoso/genética; Proteínas de Homeodomínio/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dioxigenases / Insuficiência Renal / Morte Perinatal Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Pregnancy Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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