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Blocking AMPK ß1 myristoylation enhances AMPK activity and protects mice from high-fat diet-induced obesity and hepatic steatosis.
Neopane, Katyayanee; Kozlov, Natalie; Negoita, Florentina; Murray-Segal, Lisa; Brink, Robert; Hoque, Ashfaqul; Ovens, Ashley J; Tjin, Gavin; McAloon, Luke M; Yu, Dingyi; Ling, Naomi X Y; Sanders, Matthew J; Oakhill, Jonathan S; Scott, John W; Steinberg, Gregory R; Loh, Kim; Kemp, Bruce E; Sakamoto, Kei; Galic, Sandra.
Afiliação
  • Neopane K; Nestlé Institute of Health Sciences, Nestlé Research, Société des Produits Nestlé S.A., 1015 Lausanne, Switzerland; School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne 1015, Switzerland.
  • Kozlov N; Protein Chemistry and Metabolism, St. Vincent's Institute of Medical Research, Melbourne, VIC 3065, Australia.
  • Negoita F; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen 2200, Denmark.
  • Murray-Segal L; Protein Chemistry and Metabolism, St. Vincent's Institute of Medical Research, Melbourne, VIC 3065, Australia.
  • Brink R; Garvan Institute of Medical Research and St. Vincent's Clinical School, University of New South Wales, Sydney, Darlinghurst, NSW 2010, Australia.
  • Hoque A; Metabolic Signalling, St. Vincent's Institute of Medical Research, Fitzroy, VIC 3065, Australia.
  • Ovens AJ; Metabolic Signalling, St. Vincent's Institute of Medical Research, Fitzroy, VIC 3065, Australia.
  • Tjin G; Stem Cell Regulation, St. Vincent's Institute of Medical Research, Fitzroy, VIC 3065, Australia; Department of Medicine, University of Melbourne, Parkville, VIC 3010, Australia.
  • McAloon LM; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Parkville, VIC 3052, Australia.
  • Yu D; Protein Chemistry and Metabolism, St. Vincent's Institute of Medical Research, Melbourne, VIC 3065, Australia.
  • Ling NXY; Metabolic Signalling, St. Vincent's Institute of Medical Research, Fitzroy, VIC 3065, Australia.
  • Sanders MJ; Nestlé Institute of Health Sciences, Nestlé Research, Société des Produits Nestlé S.A., 1015 Lausanne, Switzerland.
  • Oakhill JS; Metabolic Signalling, St. Vincent's Institute of Medical Research, Fitzroy, VIC 3065, Australia; Department of Medicine, University of Melbourne, Parkville, VIC 3010, Australia.
  • Scott JW; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Parkville, VIC 3052, Australia; The Florey Institute of Neuroscience and Mental Health, Parkville, Melbourne, VIC 3052, Australia.
  • Steinberg GR; Centre for Metabolism, Obesity, and Diabetes Research, Departments of Medicine and Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada.
  • Loh K; Department of Medicine, University of Melbourne, Parkville, VIC 3010, Australia; Diabetes and Metabolic Disease, St. Vincent's Institute of Medical Research, Fitzroy, VIC 3065, Australia.
  • Kemp BE; Protein Chemistry and Metabolism, St. Vincent's Institute of Medical Research, Melbourne, VIC 3065, Australia; Department of Medicine, University of Melbourne, Parkville, VIC 3010, Australia; Mary McKillop Institute for Health Research, Australian Catholic University, Melbourne 3000, VIC, Australia.
  • Sakamoto K; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen 2200, Denmark. Electronic address: kei.sakamoto@sund.ku.dk.
  • Galic S; Protein Chemistry and Metabolism, St. Vincent's Institute of Medical Research, Melbourne, VIC 3065, Australia; Department of Medicine, University of Melbourne, Parkville, VIC 3010, Australia. Electronic address: sgalic@svi.edu.au.
Cell Rep ; 41(12): 111862, 2022 12 20.
Article em En | MEDLINE | ID: mdl-36543129
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Quinases Ativadas por AMP / Fígado Gorduroso Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Quinases Ativadas por AMP / Fígado Gorduroso Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article