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A genetic off-target event in a site-specific integration cell line expressing monoclonal antibody has no impact on commercial suitability.
Tevelev, Barbara; Chambers, Andre; Ghosh, Swap; Zhang, Ying; Marzili, Lisa; Rouse, Jason C; Han, Shu; Moffat, Mark; Scarcelli, John J.
Afiliação
  • Tevelev B; Cell Line Development, Biotherapeutics Pharmaceutical Sciences, Pfizer Inc., Andover, Massachusetts, USA.
  • Chambers A; Cell Line Development, Biotherapeutics Pharmaceutical Sciences, Pfizer Inc., Chesterfield, Missouri, USA.
  • Ghosh S; Cell Line Development, Biotherapeutics Pharmaceutical Sciences, Pfizer Inc., Chesterfield, Missouri, USA.
  • Zhang Y; Analytical Research and Development, Biotherapeutics Pharmaceutical Sciences, Pfizer Inc., Andover, Massachusetts, USA.
  • Marzili L; Analytical Research and Development, Biotherapeutics Pharmaceutical Sciences, Pfizer Inc., Andover, Massachusetts, USA.
  • Rouse JC; Analytical Research and Development, Biotherapeutics Pharmaceutical Sciences, Pfizer Inc., Andover, Massachusetts, USA.
  • Han S; Cell Line Development, Biotherapeutics Pharmaceutical Sciences, Pfizer Inc., Andover, Massachusetts, USA.
  • Moffat M; Cell Line Development, Biotherapeutics Pharmaceutical Sciences, Pfizer Inc., Chesterfield, Missouri, USA.
  • Scarcelli JJ; Cell Line Development, Biotherapeutics Pharmaceutical Sciences, Pfizer Inc., Andover, Massachusetts, USA.
Biotechnol Prog ; 39(2): e3320, 2023 03.
Article em En | MEDLINE | ID: mdl-36545889
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anticorpos Monoclonais Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anticorpos Monoclonais Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article