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Allosteric Activation of 15-Lipoxygenase-1 by Boswellic Acid Induces the Lipid Mediator Class Switch to Promote Resolution of Inflammation.
Börner, Friedemann; Pace, Simona; Jordan, Paul M; Gerstmeier, Jana; Gomez, Mario; Rossi, Antonietta; Gilbert, Nathaniel C; Newcomer, Marcia E; Werz, Oliver.
Afiliação
  • Börner F; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich-Schiller-University Jena, Philosophenweg 14, 07743, Jena, Germany.
  • Pace S; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich-Schiller-University Jena, Philosophenweg 14, 07743, Jena, Germany.
  • Jordan PM; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich-Schiller-University Jena, Philosophenweg 14, 07743, Jena, Germany.
  • Gerstmeier J; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich-Schiller-University Jena, Philosophenweg 14, 07743, Jena, Germany.
  • Gomez M; Evonik Operations GmbH, Kirschenallee 45, 64293, Darmstadt, Germany.
  • Rossi A; Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via D. Montesano 49, Naples, I-80131, Italy.
  • Gilbert NC; Department of Biological Sciences, Louisiana State University, 202 Life Science Building, Baton Rouge, LA, 70803, USA.
  • Newcomer ME; Department of Biological Sciences, Louisiana State University, 202 Life Science Building, Baton Rouge, LA, 70803, USA.
  • Werz O; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich-Schiller-University Jena, Philosophenweg 14, 07743, Jena, Germany.
Adv Sci (Weinh) ; 10(6): e2205604, 2023 02.
Article em En | MEDLINE | ID: mdl-36567268
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Araquidonato 15-Lipoxigenase / Lipoxigenase Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Araquidonato 15-Lipoxigenase / Lipoxigenase Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article