The dichloromethane extract of Callicarpa longissima rich in diterpenoid phenols exerts anti-inflammatory effect via inhibiting the TLR4/NF-&#954;B signaling pathway.

Li, Lian-Chun; Fu, Yu-Xia; Ning, De-Sheng; Yu, Ling-Ling; Zou, Zhi-Qi; Pan, Zheng-Hong

The dichloromethane extract of Callicarpa longissima rich in diterpenoid phenols exerts anti-inflammatory effect via inhibiting the TLR4/NF-κB signaling pathway.

Li, Lian-Chun; Fu, Yu-Xia; Ning, De-Sheng; Yu, Ling-Ling; Zou, Zhi-Qi; Pan, Zheng-Hong.

Afiliação

Li LC; Guangxi Key Laboratory of Plant Functional Phytochemicals and Sustainable Utilization, Guangxi Institute of Botany, Chinese Academy of Sciences, Guilin, 541006, China. Electronic address: llc@gxib.cn.
Fu YX; Guangxi Key Laboratory of Plant Functional Phytochemicals and Sustainable Utilization, Guangxi Institute of Botany, Chinese Academy of Sciences, Guilin, 541006, China. Electronic address: 787835998@qq.com.
Ning DS; Guangxi Key Laboratory of Plant Functional Phytochemicals and Sustainable Utilization, Guangxi Institute of Botany, Chinese Academy of Sciences, Guilin, 541006, China. Electronic address: ndsh@gxib.cn.
Yu LL; Guangxi Key Laboratory of Plant Functional Phytochemicals and Sustainable Utilization, Guangxi Institute of Botany, Chinese Academy of Sciences, Guilin, 541006, China. Electronic address: 646832929@qq.com.
Zou ZQ; Guangxi Key Laboratory of Plant Functional Phytochemicals and Sustainable Utilization, Guangxi Institute of Botany, Chinese Academy of Sciences, Guilin, 541006, China. Electronic address: 1138416496@qq.com.
Pan ZH; Guangxi Key Laboratory of Plant Functional Phytochemicals and Sustainable Utilization, Guangxi Institute of Botany, Chinese Academy of Sciences, Guilin, 541006, China. Electronic address: pan7260@126.com.

J Ethnopharmacol ; 305: 116124, 2023 Apr 06.

Article em En | MEDLINE | ID: mdl-36587880

Assuntos

Callicarpa; Diterpenos; Animais; Camundongos; NF-kappa B/metabolismo; Inibidor de NF-kappaB alfa/metabolismo; Cloreto de Metileno/efeitos adversos; Interleucina-6/metabolismo; Carragenina/farmacologia; Fator de Necrose Tumoral alfa/metabolismo; Receptor 4 Toll-Like/metabolismo; Lipopolissacarídeos/farmacologia; Simulação de Acoplamento Molecular; Transdução de Sinais; Anti-Inflamatórios/efeitos adversos; Diterpenos/farmacologia; Edema/induzido quimicamente; Edema/tratamento farmacológico

Palavras-chave

Anti-inflammatory; Callicarpa longissima; Dichloromethane extract; Diterpenoid phenols; TLR4/NF-κB

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Callicarpa / Diterpenos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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