A dsRNA-binding mutant reveals only a minor role of exonuclease activity in interferon antagonism by the arenavirus nucleoprotein.

Bohn, Patrick; Waßmann, Irke; Wendt, Lisa; Leske, Anne; Hoenen, Thomas; Tews, Birke A; Groseth, Allison

Bohn, Patrick; Waßmann, Irke; Wendt, Lisa; Leske, Anne; Hoenen, Thomas; Tews, Birke A; Groseth, Allison.

Afiliação

Bohn P; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.
Waßmann I; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.
Wendt L; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.
Leske A; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.
Hoenen T; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.
Tews BA; Institute of Infectology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.
Groseth A; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.

PLoS Pathog ; 19(1): e1011049, 2023 01.

Article em En | MEDLINE | ID: mdl-36603036

Assuntos

Arenavirus; Arenavirus/genética; Interferons; Nucleoproteínas/genética; Nucleoproteínas/metabolismo; Quinase I-kappa B; Exonucleases/genética; RNA

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Arenavirus Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Arenavirus Idioma: En Ano de publicação: 2023 Tipo de documento: Article