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Non-hereditary early onset gastric cancer: An unmet medical need.
Petrillo, Angelica; Federico, Piera; Marte, Gianpaolo; Liguori, Carlo; Seeber, Andreas; Ottaviano, Margaret; Tufo, Andrea; Daniele, Bruno.
Afiliação
  • Petrillo A; Medical Oncology Unit, Ospedale del Mare, 80147 Napoli, Italy. Electronic address: angeli.petrillo@gmail.com.
  • Federico P; Medical Oncology Unit, Ospedale del Mare, 80147 Napoli, Italy.
  • Marte G; Surgical Unit, Ospedale del Mare, 80147 Napoli, Italy.
  • Liguori C; Department of Radiology, Ospedale del Mare, 80147 Naples, Italy.
  • Seeber A; Department of Hematology and Oncology, Comprehensive Cancer Center Innsbruck, Medical University of Innsbruck, Innsbruck, Austria.
  • Ottaviano M; Medical Oncology Unit, Ospedale del Mare, 80147 Napoli, Italy.
  • Tufo A; Surgical Unit, Ospedale del Mare, 80147 Napoli, Italy.
  • Daniele B; Medical Oncology Unit, Ospedale del Mare, 80147 Napoli, Italy.
Curr Opin Pharmacol ; 68: 102344, 2023 02.
Article em En | MEDLINE | ID: mdl-36608410
Gastric cancer (GC) is a lethal disease and the diagnosis in the young population is a major challenge from both individual and social point of views. Early-onset GC accounts for ∼5% of GC; among them, 3% are part of a hereditary syndrome and the majority are sporadic. However, even if the early-onset forms were less frequent in the past, the increasing number in the last decades has improved the interest and awareness of them in the society and in the scientific community. In particular, the different behaviour and characteristics of early-onset GC suggest that it is a completely different entity, which requires a tailored and personalized management. Here we provide an updated overview about non-hereditary early-onset GC, which is an unmet clinical need today, along with future perspectives in this field.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article