Pilot testing and optimization of a larval fathead minnow high throughput transcriptomics assay.

Villeneuve, Daniel L; Le, Michelle; Hazemi, Monique; Biales, Adam; Bencic, David C; Bush, Kendra; Flick, Robert; Martinson, John; Morshead, Mackenzie; Rodriguez, Kelvin Santana; Vitense, Kelsey; Flynn, Kevin

Villeneuve, Daniel L; Le, Michelle; Hazemi, Monique; Biales, Adam; Bencic, David C; Bush, Kendra; Flick, Robert; Martinson, John; Morshead, Mackenzie; Rodriguez, Kelvin Santana; Vitense, Kelsey; Flynn, Kevin.

Afiliação

Villeneuve DL; US Environmental Protection Agency, Great Lakes Toxicology and Ecology Division, Duluth, MN 55804, USA.
Le M; Oak Ridge Institute for Science and Education (ORISE) Research Participant, US Environmental Protection Agency Great Lakes Toxicology and Ecology Division, Duluth, MN 55804, USA.
Hazemi M; Oak Ridge Institute for Science and Education (ORISE) Research Participant, US Environmental Protection Agency Great Lakes Toxicology and Ecology Division, Duluth, MN 55804, USA.
Biales A; US Environmental Protection Agency, Great Lakes Toxicology and Ecology Division, Cincinnati, OH 45220, USA.
Bencic DC; US Environmental Protection Agency, Great Lakes Toxicology and Ecology Division, Cincinnati, OH 45220, USA.
Bush K; Oak Ridge Institute for Science and Education (ORISE) Research Participant, US Environmental Protection Agency Great Lakes Toxicology and Ecology Division, Duluth, MN 55804, USA.
Flick R; US Environmental Protection Agency, Great Lakes Toxicology and Ecology Division, Cincinnati, OH 45220, USA.
Martinson J; US Environmental Protection Agency, Great Lakes Toxicology and Ecology Division, Cincinnati, OH 45220, USA.
Morshead M; Oak Ridge Institute for Science and Education (ORISE) Research Participant, US Environmental Protection Agency Great Lakes Toxicology and Ecology Division, Duluth, MN 55804, USA.
Rodriguez KS; Oak Ridge Institute for Science and Education (ORISE) Research Participant, US Environmental Protection Agency Great Lakes Toxicology and Ecology Division, Duluth, MN 55804, USA.
Vitense K; US Environmental Protection Agency, Scientific Computing and Data Curation Division, Duluth, MN 55804, USA.
Flynn K; US Environmental Protection Agency, Great Lakes Toxicology and Ecology Division, Duluth, MN 55804, USA.

Curr Res Toxicol ; 4: 100099, 2023.

Article em En | MEDLINE | ID: mdl-36619288

Palavras-chave

BMD, Benchmark dose; Benchmark dose; Computational toxicology; DEGs, Differentially expressed genes; ECOTOX knowledgebase; Fish; HTTr, High throughput transcriptomics; RIN, RNA integrity number; RNA sequencing; RNAseq, RNA sequencing; SSRI, Selective serotonin reuptake inhibitor; ToxCast, US EPA Toxicity Forecaster; Transcriptomics-based point of departure; cDNA, Complementary DNA; eco-HTTr, Ecological high throughput transcriptomics; tPOD, Transcriptomics-based point of departure

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article