An Investigation into the In Vitro Metabolic Stability of Aryl Sulfonyl Fluorides for their Application in Medicinal Chemistry and Radiochemistry.

King, Andrew T; Matesic, Lidia; Keaveney, Sinead T; Jamie, Joanne F

King, Andrew T; Matesic, Lidia; Keaveney, Sinead T; Jamie, Joanne F.

Afiliação

King AT; School of Natural Sciences, Wallumattagal Campus, Macquarie University, North Ryde, New South Wales 2109, Australia.
Matesic L; Australian Nuclear Science and Technology Organisation, New Illawarra Rd, Lucas Heights, New South Wales 2234, Australia.
Keaveney ST; School of Natural Sciences, Wallumattagal Campus, Macquarie University, North Ryde, New South Wales 2109, Australia.
Jamie JF; School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, New South Wales 2522, Australia.

Mol Pharm ; 20(2): 1061-1071, 2023 02 06.

Article em En | MEDLINE | ID: mdl-36638322

Assuntos

Química Farmacêutica; Fluoretos; Animais; Ratos; Radioquímica/métodos; Fluoretos/química; Ácidos Sulfínicos

Palavras-chave

defluorination; metabolic stability; radiochemistry; sulfonyl fluorides

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Química Farmacêutica / Fluoretos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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