Inhibiting O-GlcNAcylation impacts p38 and Erk1/2 signaling and perturbs cardiomyocyte hypertrophy.

Papanicolaou, Kyriakos N; Jung, Jessica; Ashok, Deepthi; Zhang, Wenxi; Modaressanavi, Amir; Avila, Eddie; Foster, D Brian; Zachara, Natasha E; O'Rourke, Brian

Papanicolaou, Kyriakos N; Jung, Jessica; Ashok, Deepthi; Zhang, Wenxi; Modaressanavi, Amir; Avila, Eddie; Foster, D Brian; Zachara, Natasha E; O'Rourke, Brian.

Afiliação

Papanicolaou KN; Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Electronic address: kyriakos@jhu.edu.
Jung J; Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Ashok D; Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Zhang W; Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Modaressanavi A; Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Avila E; Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Foster DB; Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Zachara NE; Department of Biological Chemistry, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
O'Rourke B; Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Electronic address: bor@jhmi.edu.

J Biol Chem ; 299(3): 102907, 2023 03.

Article em En | MEDLINE | ID: mdl-36642184

Assuntos

Miócitos Cardíacos; Transdução de Sinais; Humanos; Miócitos Cardíacos/metabolismo; Transdução de Sinais/fisiologia; Fosforilação; Hipertrofia/metabolismo; Proteínas/metabolismo; N-Acetilglucosaminiltransferases/genética; N-Acetilglucosaminiltransferases/metabolismo; Acetilglucosamina/metabolismo

Palavras-chave

Creb; Gata4; Hsp27; Hsp90; MKK3/6; OGA; OGT; OSMI; TMG; Tab1

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Miócitos Cardíacos Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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