A Nucleophilic Activity-Based Probe Enables Profiling of PLP-Dependent Enzymes.

Brody, Scott I; Buonomo, Joseph A; Orimoloye, Moyosore O; Jia, Ziyi; Sharma, Sachin; Brown, Christopher D; Baughn, Anthony D; Aldrich, Courtney C

Brody, Scott I; Buonomo, Joseph A; Orimoloye, Moyosore O; Jia, Ziyi; Sharma, Sachin; Brown, Christopher D; Baughn, Anthony D; Aldrich, Courtney C.

Afiliação

Brody SI; Department of Medicinal Chemistry, University of Minnesota-Twin Cities, 308 Harvard Street SE, Minneapolis, MN 55455, USA.
Buonomo JA; Department of Medicinal Chemistry, University of Minnesota-Twin Cities, 308 Harvard Street SE, Minneapolis, MN 55455, USA.
Orimoloye MO; Department of Medicinal Chemistry, University of Minnesota-Twin Cities, 308 Harvard Street SE, Minneapolis, MN 55455, USA.
Jia Z; Department of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Sharma S; Department of Medicinal Chemistry, University of Minnesota-Twin Cities, 308 Harvard Street SE, Minneapolis, MN 55455, USA.
Brown CD; Department of Medicinal Chemistry, University of Minnesota-Twin Cities, 308 Harvard Street SE, Minneapolis, MN 55455, USA.
Baughn AD; Department of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Aldrich CC; Department of Medicinal Chemistry, University of Minnesota-Twin Cities, 308 Harvard Street SE, Minneapolis, MN 55455, USA.

Chembiochem ; 24(7): e202200669, 2023 04 03.

Article em En | MEDLINE | ID: mdl-36652345

Assuntos

Fosfato de Piridoxal; Fosfato de Piridoxal/química; Modelos Moleculares; Espectrometria de Massas

Palavras-chave

PLP-dependent enzymes; activity-based protein profilin; chemical genetics; chemoproteomics; probes

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfato de Piridoxal Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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