Inhibition of PI3K/Akt/mTOR signaling by NDRG2 contributes to neuronal apoptosis and autophagy in ischemic stroke.

Wang, Yuanyuan; Wang, Bo; Liu, Yuanyuan; Guo, Yansong; Lu, Hui; Liu, Xiqi

Wang, Yuanyuan; Wang, Bo; Liu, Yuanyuan; Guo, Yansong; Lu, Hui; Liu, Xiqi.

Afiliação

Wang Y; Department Five of Neurology, Cangzhou Central Hospital, Cangzhou, 061000, Hebei, PR China. Electronic address: yuanyuanW113@163.com.
Wang B; Department Five of Neurology, Cangzhou Central Hospital, Cangzhou, 061000, Hebei, PR China.
Liu Y; Department Five of Neurology, Cangzhou Central Hospital, Cangzhou, 061000, Hebei, PR China.
Guo Y; Department of Urology, Cangzhou People's Hospital, Cangzhou, 061000, Hebei, PR China.
Lu H; Department Five of Neurology, Cangzhou Central Hospital, Cangzhou, 061000, Hebei, PR China.
Liu X; Department Five of Neurology, Cangzhou Central Hospital, Cangzhou, 061000, Hebei, PR China.

J Stroke Cerebrovasc Dis ; 32(3): 106984, 2023 Mar.

Article em En | MEDLINE | ID: mdl-36652790

Assuntos

AVC Isquêmico; Proteínas Proto-Oncogênicas c-akt; Ratos; Camundongos; Animais; Proteínas Proto-Oncogênicas c-akt/metabolismo; Fosfatidilinositol 3-Quinases/metabolismo; Sirolimo/farmacologia; Serina-Treonina Quinases TOR/metabolismo; Apoptose; Autofagia; Mamíferos/metabolismo; Proteínas do Tecido Nervoso

Palavras-chave

Apoptosis; Autophagy; Ischemic stroke; NDRG2; The PI3K/Akt/mTOR pathway

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas c-akt / AVC Isquêmico Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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