[Research progress of Eubacterium and its metabolite short-chain fatty acids in regulating type 2 diabetes mellitus].
Zhonghua Yu Fang Yi Xue Za Zhi
; 57(1): 120-124, 2023 Jan 06.
Article
em Zh
| MEDLINE
| ID: mdl-36655268
Intestinal flora and its metabolites are closely related to the progression of type 2 diabetes mellitus(T2DM). Eubacterium is one of the dominant intestinal flora, and its metabolites short-chain fatty acids (SCFAs) play a leading role in regulating intestinal metabolic balance. It has been reported that SCFAs can regulate the secretion of glucagon-like peptide-1, improve the function of pancreatic ß cells, participate in bile acids metabolism and regulate the production of inflammatory factors in T2DM. Based on the above research background, this article mainly reviews the relationship between Eubacterium and its metabolite SCFAs and T2DM and its regulatory mechanism.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Diabetes Mellitus Tipo 2
/
Microbioma Gastrointestinal
Limite:
Humans
Idioma:
Zh
Ano de publicação:
2023
Tipo de documento:
Article