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Mitochondria-Targeted Triphenylphosphonium-Hydroxytyrosol Prevents Lipotoxicity-Induced Endothelial Injury by Enhancing Mitochondrial Function and Redox Balance via Promoting FoxO1 and Nrf2 Nuclear Translocation and Suppressing Inflammation via Inhibiting p38/NF-кB Pathway.
Liu, Xuyun; Gao, Jing; Yan, Yizhen; Georgiou, Eleftheria A; Lou, Jing; Feng, Mengya; Zhang, Xing; Gao, Feng; Liu, Jiankang; Kostakis, Ioannis K; Zhao, Lin.
Afiliação
  • Liu X; Center for Mitochondrial Biology and Medicine, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology and Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, 710049, China.
  • Gao J; Center for Mitochondrial Biology and Medicine, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology and Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, 710049, China.
  • Yan Y; Key Laboratory of Ministry of Education, School of Aerospace Medicine, Fourth Military Medical University, Xi'an 710032, China.
  • Georgiou EA; Faculty of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Panepistimiopolis-Zografou, 15771 Athens, Greece.
  • Lou J; Center for Mitochondrial Biology and Medicine, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology and Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, 710049, China.
  • Feng M; Center for Mitochondrial Biology and Medicine, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology and Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, 710049, China.
  • Zhang X; Key Laboratory of Ministry of Education, School of Aerospace Medicine, Fourth Military Medical University, Xi'an 710032, China.
  • Gao F; Key Laboratory of Ministry of Education, School of Aerospace Medicine, Fourth Military Medical University, Xi'an 710032, China.
  • Liu J; Center for Mitochondrial Biology and Medicine, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology and Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, 710049, China.
  • Kostakis IK; School of Life Sciences, University of Health and Rehabilitation Sciences, Qingdao 266071, China.
  • Zhao L; Faculty of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Panepistimiopolis-Zografou, 15771 Athens, Greece.
Antioxidants (Basel) ; 12(1)2023 Jan 11.
Article em En | MEDLINE | ID: mdl-36671037
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article