Iron Deprivation by Oral Deferoxamine Application Alleviates Acute Campylobacteriosis in a Clinical Murine <i>Campylobacter jejuni</i> Infection Model.

Bereswill, Stefan; Mousavi, Soraya; Weschka, Dennis; Buczkowski, Agnes; Schmidt, Sebastian; Heimesaat, Markus M

Iron Deprivation by Oral Deferoxamine Application Alleviates Acute Campylobacteriosis in a Clinical Murine Campylobacter jejuni Infection Model.

Bereswill, Stefan; Mousavi, Soraya; Weschka, Dennis; Buczkowski, Agnes; Schmidt, Sebastian; Heimesaat, Markus M.

Afiliação

Bereswill S; Gastrointestinal Microbiology Research Group, Institute of Microbiology, Infectious Diseases and Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 12203 Berlin, Germany.
Mousavi S; Gastrointestinal Microbiology Research Group, Institute of Microbiology, Infectious Diseases and Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 12203 Berlin, Germany.
Weschka D; Gastrointestinal Microbiology Research Group, Institute of Microbiology, Infectious Diseases and Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 12203 Berlin, Germany.
Buczkowski A; Gastrointestinal Microbiology Research Group, Institute of Microbiology, Infectious Diseases and Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 12203 Berlin, Germany.
Schmidt S; Hofmann & Sommer GmbH und Co. KG, Büro Berlin, 12489 Berlin, Germany.
Heimesaat MM; Gastrointestinal Microbiology Research Group, Institute of Microbiology, Infectious Diseases and Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 12203 Berlin, Germany.

Biomolecules ; 13(1)2022 12 29.

Article em En | MEDLINE | ID: mdl-36671455

Assuntos

Infecções por Campylobacter; Campylobacter jejuni; Enterocolite; Animais; Camundongos; Desferroxamina/farmacologia; Desferroxamina/uso terapêutico; Infecções por Campylobacter/tratamento farmacológico; Enterocolite/tratamento farmacológico; Intestinos

Palavras-chave

Campylobacter jejuni; acute campylobacteriosis model; desferoxamine; disease-modifying properties; enteropathogenic infection; host-pathogen interaction; immune-modulatory effects; iron binding; microbiota-depleted IL-10−/− mice; natural antibiotics-independent compounds; preclinical intervention study; reactive oxygen species

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por Campylobacter / Campylobacter jejuni / Enterocolite Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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