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Investigating the potential anticancer activities of antibiotics as topoisomerase II inhibitors and DNA intercalators: in vitro, molecular docking, molecular dynamics, and SAR studies.
Farouk, Faten; Elmaaty, Ayman Abo; Elkamhawy, Ahmed; Tawfik, Haytham O; Alnajjar, Radwan; Abourehab, Mohammed A S; Saleh, Mohamed A; Eldehna, Wagdy M; Al-Karmalawy, Ahmed A.
Afiliação
  • Farouk F; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ahram Canadian University, Giza, Egypt.
  • Elmaaty AA; Department of Medicinal Chemistry, Faculty of Pharmacy, Port Said University, Port Said, Egypt.
  • Elkamhawy A; BK21 FOUR Team and Integrated Research Institute for Drug Development, College of Pharmacy, Dongguk University-Seoul, Goyang, Republic of Korea.
  • Tawfik HO; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
  • Alnajjar R; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Tanta University, Tanta, Egypt.
  • Abourehab MAS; Department of Chemistry, Faculty of Science, University of Benghazi, Benghazi, Libya.
  • Saleh MA; PharmD, Faculty of Pharmacy, Libyan International Medical University, Benghazi, Libya.
  • Eldehna WM; Department of Chemistry, University of Cape Town, Rondebosch, South Africa.
  • Al-Karmalawy AA; Department of Pharmaceutics, Faculty of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia.
J Enzyme Inhib Med Chem ; 38(1): 2171029, 2023 Dec.
Article em En | MEDLINE | ID: mdl-36701269
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores da Topoisomerase II / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores da Topoisomerase II / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article