Bromodomain-containing protein 4 (BRD4): a key player in inflammatory bowel disease and potential to inspire epigenetic therapeutics.

Ma, Zonghui; Bolinger, Andrew A; Zhou, Jia; Tian, Bing

Ma, Zonghui; Bolinger, Andrew A; Zhou, Jia; Tian, Bing.

Afiliação

Ma Z; Chemical Biology Program, Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, TX, USA.
Bolinger AA; Chemical Biology Program, Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, TX, USA.
Zhou J; Chemical Biology Program, Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, TX, USA.
Tian B; Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, USA.

Expert Opin Ther Targets ; 27(1): 1-7, 2023 01.

Article em En | MEDLINE | ID: mdl-36710583

Assuntos

Doenças Inflamatórias Intestinais; Neoplasias; Humanos; Fatores de Transcrição/genética; Proteínas Nucleares; Proteínas de Ciclo Celular/genética; Neoplasias/tratamento farmacológico; Epigênese Genética

Palavras-chave

Bromodomain-containing protein 4 (BRD4); Crohn's disease (CD); anti-inflammatory therapy; drug target; epigenetics; inflammatory bowel disease (IBD); nuclear factor-κB (nfκb); ulcerative colitis (UC)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Inflamatórias Intestinais / Neoplasias Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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