Introducing Aliphatic Fluoropeptides: Perspectives on Folding Properties, Membrane Partition and Proteolytic Stability.

Hohmann, Thomas; Chowdhary, Suvrat; Ataka, Kenichi; Er, Jasmin; Dreyhsig, Gesa Heather; Heberle, Joachim; Koksch, Beate

Hohmann, Thomas; Chowdhary, Suvrat; Ataka, Kenichi; Er, Jasmin; Dreyhsig, Gesa Heather; Heberle, Joachim; Koksch, Beate.

Afiliação

Hohmann T; Institute of Chemistry and Biochemistry, Freie Universität Berlin, Arnimallee 20, 14195, Berlin, Germany.
Chowdhary S; Institute of Chemistry and Biochemistry, Freie Universität Berlin, Arnimallee 20, 14195, Berlin, Germany.
Ataka K; Department of Physics, Freie Universität Berlin, Arnimallee 14, 14195, Berlin, Germany.
Er J; Institute of Chemistry and Biochemistry, Freie Universität Berlin, Arnimallee 20, 14195, Berlin, Germany.
Dreyhsig GH; Institute of Chemistry and Biochemistry, Freie Universität Berlin, Arnimallee 20, 14195, Berlin, Germany.
Heberle J; Department of Physics, Freie Universität Berlin, Arnimallee 14, 14195, Berlin, Germany.
Koksch B; Institute of Chemistry and Biochemistry, Freie Universität Berlin, Arnimallee 20, 14195, Berlin, Germany.

Chemistry ; 29(23): e202203860, 2023 Apr 21.

Article em En | MEDLINE | ID: mdl-36722398

Assuntos

Aminoácidos; Peptídeos; Peptídeos/química; Aminoácidos/química; Peptídeo Hidrolases; Bicamadas Lipídicas/química; Proteólise; Dicroísmo Circular; Dobramento de Proteína

Palavras-chave

fluorinated biomaterials; fluoropeptides; fluorous amino acids; foldamers; membrane disruption

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos / Aminoácidos Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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