Developing H3K27M mutant selective radiosensitization strategies in diffuse intrinsic pontine glioma.

Parsels, Leslie A; Wahl, Daniel R; Koschmann, Carl; Morgan, Meredith A; Zhang, Qiang

Parsels, Leslie A; Wahl, Daniel R; Koschmann, Carl; Morgan, Meredith A; Zhang, Qiang.

Afiliação

Parsels LA; Department of Radiation Oncology, Rogel Cancer Center, University of Michigan Medical School, 1301 Catherine Street, Ann Arbor, MI, 48109, USA.
Wahl DR; Department of Radiation Oncology, Rogel Cancer Center, University of Michigan Medical School, 1301 Catherine Street, Ann Arbor, MI, 48109, USA.
Koschmann C; Department of Pediatrics, Division of Pediatric Hematology-Oncology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Morgan MA; Department of Radiation Oncology, Rogel Cancer Center, University of Michigan Medical School, 1301 Catherine Street, Ann Arbor, MI, 48109, USA. Electronic address: mmccrack@med.umich.edu.
Zhang Q; Department of Radiation Oncology, Rogel Cancer Center, University of Michigan Medical School, 1301 Catherine Street, Ann Arbor, MI, 48109, USA. Electronic address: qiangz@med.umich.edu.

Neoplasia ; 37: 100881, 2023 03.

Article em En | MEDLINE | ID: mdl-36724689

Assuntos

Neoplasias do Tronco Encefálico; Glioma Pontino Intrínseco Difuso; Glioma; Adolescente; Humanos; Criança; Glioma Pontino Intrínseco Difuso/genética; Glioma/genética; Recidiva Local de Neoplasia; Histonas/genética; Mutação; Neoplasias do Tronco Encefálico/genética; Neoplasias do Tronco Encefálico/patologia

Palavras-chave

DIPG; DNA damage response; H3K27M; Immunotherapy; Radiotherapy; Tumor immunology

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias do Tronco Encefálico / Glioma Pontino Intrínseco Difuso / Glioma Limite: Adolescent / Child / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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