When IL-17 gets on your nerves.

Iliev, Iliyan D; Lin, Woan-Yu; Gaffen, Sarah L

Iliev, Iliyan D; Lin, Woan-Yu; Gaffen, Sarah L.

Afiliação

Iliev ID; Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY 10021, USA. Electronic address: iliev@med.cornell.edu.
Lin WY; Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY 10021, USA.
Gaffen SL; Division of Rheumatology & Clinical Immunology, Department of Medicine University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: sarah.gaffen@pitt.edu.

Cell ; 186(3): 466-468, 2023 02 02.

Article em En | MEDLINE | ID: mdl-36736299

ABSTRACT

ABSTRACT

Microbiota-induced IL-17 production mediates CNS processes and animal behavior. However, its role on the peripheral nervous system (PNS) remains largely unknown. Enamorado et al. demonstrate that commensal-specific Th17 cells are recalled following tissue injury to support local nerve regeneration, a process orchestrated by IL-17 signaling on peripheral neurons.

Assuntos

Sistema Nervoso Central; Interleucina-17; Animais; Sistema Nervoso Periférico; Regeneração Nervosa/fisiologia; Transdução de Sinais; Nervos Periféricos; Axônios/fisiologia

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistema Nervoso Central / Interleucina-17 Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google