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Sulfamate Acetamides as Self-Immolative Electrophiles for Covalent Ligand-Directed Release Chemistry.
Reddi, Rambabu N; Rogel, Adi; Gabizon, Ronen; Rawale, Dattatraya Gautam; Harish, Battu; Marom, Shir; Tivon, Barr; Arbel, Yamit Shorer; Gurwicz, Neta; Oren, Roni; David, Keren; Liu, Jingjing; Duberstein, Shirly; Itkin, Maxim; Malitsky, Sergey; Barr, Haim; Katz, Ben-Zion; Herishanu, Yair; Shachar, Idit; Shulman, Ziv; London, Nir.
Afiliação
  • Reddi RN; Dept. of Chemical and Structural Biology, The Weizmann Institute of Science, Rehovot 7610001, Israel.
  • Rogel A; Dept. of Chemical and Structural Biology, The Weizmann Institute of Science, Rehovot 7610001, Israel.
  • Gabizon R; Dept. of Chemical and Structural Biology, The Weizmann Institute of Science, Rehovot 7610001, Israel.
  • Rawale DG; Dept. of Chemical and Structural Biology, The Weizmann Institute of Science, Rehovot 7610001, Israel.
  • Harish B; Dept. of Chemical and Structural Biology, The Weizmann Institute of Science, Rehovot 7610001, Israel.
  • Marom S; Dept. of Chemical and Structural Biology, The Weizmann Institute of Science, Rehovot 7610001, Israel.
  • Tivon B; Dept. of Chemical and Structural Biology, The Weizmann Institute of Science, Rehovot 7610001, Israel.
  • Arbel YS; Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv 6997801, Israel.
  • Gurwicz N; Dept. of Systems Immunology, The Weizmann Institute of Science, Rehovot 7610001, Israel.
  • Oren R; Department of Veterinary Resources, The Weizmann Institute of Science, Rehovot 7610001, Israel.
  • David K; Dept. of Systems Immunology, The Weizmann Institute of Science, Rehovot 7610001, Israel.
  • Liu J; Dept. of Systems Immunology, The Weizmann Institute of Science, Rehovot 7610001, Israel.
  • Duberstein S; Wohl Institute for Drug Discovery of the Nancy and Stephen Grand Israel National Center for Personalized Medicine, The Weizmann Institute of Science, Rehovot 7610001, Israel.
  • Itkin M; Life Sciences Core Facilities, The Weizmann Institute of Science, Rehovot 7610001, Israel.
  • Malitsky S; Life Sciences Core Facilities, The Weizmann Institute of Science, Rehovot 7610001, Israel.
  • Barr H; Wohl Institute for Drug Discovery of the Nancy and Stephen Grand Israel National Center for Personalized Medicine, The Weizmann Institute of Science, Rehovot 7610001, Israel.
  • Katz BZ; Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv 6997801, Israel.
  • Herishanu Y; Department of Hematology, Tel Aviv Sourasky Medical Center, Tel Aviv 6423906, Israel.
  • Shachar I; Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv 6997801, Israel.
  • Shulman Z; Department of Hematology, Tel Aviv Sourasky Medical Center, Tel Aviv 6423906, Israel.
  • London N; Dept. of Systems Immunology, The Weizmann Institute of Science, Rehovot 7610001, Israel.
J Am Chem Soc ; 145(6): 3346-3360, 2023 02 15.
Article em En | MEDLINE | ID: mdl-36738297
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores de Proteínas Quinases / Acetamidas Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores de Proteínas Quinases / Acetamidas Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article