Programmed death ligand 1 regulates epithelial-mesenchymal transition and cancer stem cell phenotypes in hepatocellular carcinoma through the serum and glucocorticoid kinase 2/ß-catenin signaling pathway.

Kong, Xin; Peng, Hong; Liu, Peng; Fu, Xiao; Wang, Ni; Zhang, Dazhi

Kong, Xin; Peng, Hong; Liu, Peng; Fu, Xiao; Wang, Ni; Zhang, Dazhi.

Afiliação

Kong X; Department of Infectious Diseases, Key Laboratory of Molecular Biology for Infectious Diseases, Institute for Viral Hepatitis, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Peng H; Bishan Hospital of Chongqing, Bishan Hospital of Chongqing Medical University, Chongqing, China.
Liu P; Department of Otolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Fu X; Department of Infectious Diseases, Key Laboratory of Molecular Biology for Infectious Diseases, Institute for Viral Hepatitis, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Wang N; Department of Infectious Diseases, Key Laboratory of Molecular Biology for Infectious Diseases, Institute for Viral Hepatitis, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Zhang D; Department of Infectious Diseases, Key Laboratory of Molecular Biology for Infectious Diseases, Institute for Viral Hepatitis, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Cancer Sci ; 114(6): 2265-2276, 2023 Jun.

Article em En | MEDLINE | ID: mdl-36751987

Assuntos

Carcinoma Hepatocelular; Neoplasias Hepáticas; Animais; Camundongos; Antígeno B7-H1/metabolismo; beta Catenina/genética; Carcinoma Hepatocelular/patologia; Linhagem Celular Tumoral; Transição Epitelial-Mesenquimal; Glucocorticoides/metabolismo; Glucocorticoides/farmacologia; Neoplasias Hepáticas/patologia; Camundongos Nus; Células-Tronco Neoplásicas/metabolismo; Fenótipo; Transdução de Sinais; Humanos

Palavras-chave

CSC; EMT; PD-L1; SGK2; ß-Catenin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Neoplasias Hepáticas Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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