Regulatory B cells are reduced in the blood in patients with granulomatosis with polyangiitis, and fail to regulate T-cell IFN-Î³ production.

Appelgren, Daniel; Puli, Srinivasulu; Hellmark, Thomas; Pochard, Pierre; Pers, Jacques-Olivier; Ernerudh, Jan; Eriksson, Per; Segelmark, Mårten

Appelgren, Daniel; Puli, Srinivasulu; Hellmark, Thomas; Pochard, Pierre; Pers, Jacques-Olivier; Ernerudh, Jan; Eriksson, Per; Segelmark, Mårten.

Afiliação

Appelgren D; Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.
Puli S; Department of Clinical Sciences in Lund, Nephrology, Lund University and Skåne University Hospital, Lund, Sweden.
Hellmark T; Department of Clinical Sciences in Lund, Nephrology, Lund University and Skåne University Hospital, Lund, Sweden.
Pochard P; LBAI, UMR1227, Univ Brest, Inserm, CHU de Brest, Brest, France.
Pers JO; LBAI, UMR1227, Univ Brest, Inserm, Brest, France.
Ernerudh J; Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Eriksson P; Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Segelmark M; Department of Rheumatology, Linköping University, Linköping, Sweden.

Clin Exp Immunol ; 213(2): 190-201, 2023 07 21.

Article em En | MEDLINE | ID: mdl-36752779

Assuntos

Linfócitos B Reguladores; Granulomatose com Poliangiite; Humanos; Linfócitos B Reguladores/metabolismo; Citocinas/metabolismo; Interferon gama; Inflamação

Palavras-chave

T-cells; autoimmunity; granulomatosis with polyangiitis (GPA); immune regulation; regulatory B-cells

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Granulomatose com Poliangiite / Linfócitos B Reguladores Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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