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Development and validation of risk calculators for people with "thin" melanomas on their skin to predict the likelihood that their cancer will return: a plain language summary of publication.
Sharouni, Mary-Ann El; Lo, Serigne N; Varey, Alexander Hr; Elias, Sjoerd G; Witkamp, Arjen J; Sigurdsson, Vigfús; Suijkerbuijk, Karijn Pm; van Diest, Paul J; van Gils, Carla H; Blokx, Willeke Am; Scolyer, Richard A; Thompson, John F.
Afiliação
  • Sharouni ME; Department of Dermatology, University Medic al Center Utrecht, Utrecht University, Utrecht, the Netherlands.
  • Lo SN; Melanoma Institute Australia, The University of Sydney, North Sydney, NSW, Australia.
  • Varey AH; Melanoma Institute Australia, The University of Sydney, North Sydney, NSW, Australia.
  • Elias SG; Faculty of Medicine & Health, The University of Sydney, Sydney, NSW, Australia.
  • Witkamp AJ; Department of Dermatology, University Medic al Center Utrecht, Utrecht University, Utrecht, the Netherlands.
  • Sigurdsson V; Faculty of Medicine & Health, The University of Sydney, Sydney, NSW, Australia.
  • Suijkerbuijk KP; Department of Plastic & Reconstructive Surgery, Westmead Hospital, Sydney, NSW, Australia.
  • van Diest PJ; Julius Center for Health Sciences & Primary Care, University Medical Center Utrecht, University Utrecht, Utrecht, the Netherlands.
  • van Gils CH; Department of Surgery, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
  • Blokx WA; Department of Dermatology, University Medic al Center Utrecht, Utrecht University, Utrecht, the Netherlands.
  • Scolyer RA; Department of Medical Oncology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
  • Thompson JF; Department of Pathology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
Future Oncol ; 19(2): 97-102, 2023 Jan.
Article em En | MEDLINE | ID: mdl-36762595
WHAT IS THIS SUMMARY ABOUT?: This is a summary of an article describing the development of risk calculators for use in people who develop a type of melanoma on their skin called "thin" melanoma to predict the likelihood that their cancer will return. The article was originally published in the Journal of Clinical Oncology in 2021. HOW WERE THE CALCULATORS DEVELOPED?: Calculations were performed to predict the chance of people with thin melanomas surviving without their melanoma recurring. Three graphical prediction calculators (called nomograms) were developed, along with easy-to-use online calculators using the same underlying calculation methods. The model was developed using data for 25,930 Dutch people diagnosed with thin melanomas (called the "development set"). To test its ability to predict melanoma recurrence, it was then compared with data for 2,968 Australian people with melanoma (the "validation set"). The calculators developed in the Dutch patients were found to accurately predict the risk of melanoma recurring for people with melanoma in the Australian "validation" group. WHAT DO THE RESULTS MEAN?: The calculators provide estimates of the risk of the melanoma returning for people with thin melanomas. The easy-to-use online calculators are freely available on a smartphone, tablet or computer, and will assist in providing accurate estimates of recurrence risks for individuals with thin melanomas, allowing more intensive follow-up of those whose predicted risk of their melanoma returning is high.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Melanoma Tipo de estudo: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans País/Região como assunto: Oceania Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Melanoma Tipo de estudo: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans País/Região como assunto: Oceania Idioma: En Ano de publicação: 2023 Tipo de documento: Article