Early Fractional Ablative Laser for Skin Cancer Excision Scars: A Randomized Split-Scar Study.
Dermatol Surg
; 49(4): 338-342, 2023 04 01.
Article
em En
| MEDLINE
| ID: mdl-36763896
ABSTRACT
BACKGROUND:
Fractional ablative laser resurfacing has been shown to improve the final cosmetic appearance of surgical scars, but optimal timing is unknown.OBJECTIVE:
To compare surgical scars treated with fractional carbon dioxide (CO 2 ) laser performed on Day 0 and Day 14.METHODS:
Prospective, randomized, split-scar, physician-blinded study of 30 surgical scars on the limbs. Scars halves received fractional CO 2 laser on either Day 0 or Day 14. Scar assessment at 6 months evaluated patient preference, physician modified Manchester Scar Scale (MMSS) score, and quantitative scar analysis on histology (fractal dimension [F D ] and lacunarity [L] analysis).RESULTS:
There was no significant difference in patient assessment (54% preferred Day 0 side, 46% preferred Day 14 side, p = .58) or physician assessment (mean MMSS 8.4 for Day 0 vs 8.7 for Day 14, p = .28). Fractal dimensions were similar for both interventions (mean 1.778 for Day 0 vs 1.781 for Day 14, p = .80). Lacunarity was similar for both interventions (mean 0.368 for Day 0 vs 0.345 for Day 14, p = .44).LIMITATIONS:
Single-center study with wounds limited to limbs of skin Phototype I-II subjects; 4 of whom were lost to follow-up.CONCLUSION:
Intraoperative CO 2 laser is noninferior to Day 14 laser resurfacing for surgical scar treatment.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Cutâneas
/
Terapia a Laser
/
Lasers de Gás
Tipo de estudo:
Clinical_trials
/
Etiology_studies
/
Observational_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article