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Combination treatment of T1-44, a PRMT5 inhibitor with Vactosertib, an inhibitor of TGF-ß signaling, inhibits invasion and prolongs survival in a mouse model of pancreatic tumors.
Hong, Eunji; Barczak, Wojciech; Park, Sujin; Heo, Jin Sun; Ooshima, Akira; Munro, Shonagh; Hong, Chang Pyo; Park, Jinah; An, Haein; Park, Joon Oh; Park, Seok Hee; La Thangue, Nick B; Kim, Seong-Jin.
Afiliação
  • Hong E; GILO Institute, GILO Foundation, Seoul, Republic of Korea.
  • Barczak W; Department of Biological Sciences, Sungkyunkwan University, Suwon, Gyeonggi-do, Republic of Korea.
  • Park S; Laboratory of Cancer Biology, Department of Oncology, University of Oxford, Old Road Campus Research Building, Old Road Campus, Oxford, UK.
  • Heo JS; GILO Institute, GILO Foundation, Seoul, Republic of Korea.
  • Ooshima A; GILO Institute, GILO Foundation, Seoul, Republic of Korea.
  • Munro S; GILO Institute, GILO Foundation, Seoul, Republic of Korea.
  • Hong CP; Argonaut Therapeutics Ltd, Magdalen Centre, Oxford Science Park, Oxford, UK.
  • Park J; Theragen Bio Co., Ltd, Seongnam, Republic of Korea.
  • An H; GILO Institute, GILO Foundation, Seoul, Republic of Korea.
  • Park JO; GILO Institute, GILO Foundation, Seoul, Republic of Korea.
  • Park SH; Department of Biological Sciences, Sungkyunkwan University, Suwon, Gyeonggi-do, Republic of Korea.
  • La Thangue NB; Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
  • Kim SJ; Department of Biological Sciences, Sungkyunkwan University, Suwon, Gyeonggi-do, Republic of Korea.
Cell Death Dis ; 14(2): 93, 2023 02 10.
Article em En | MEDLINE | ID: mdl-36765032
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Carcinoma Ductal Pancreático Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Carcinoma Ductal Pancreático Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article