Opposite Modulation of the NMDA Receptor by Glycine and S-Ketamine and the Effects on Resting State EEG Gamma Activity: New Insights into the Glutamate Hypothesis of Schizophrenia.

Haaf, Moritz; Curic, Stjepan; Rauh, Jonas; Steinmann, Saskia; Mulert, Christoph; Leicht, Gregor

Haaf, Moritz; Curic, Stjepan; Rauh, Jonas; Steinmann, Saskia; Mulert, Christoph; Leicht, Gregor.

Afiliação

Haaf M; Department of Psychiatry and Psychotherapy, Psychiatry Neuroimaging Branch (PNB), University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Curic S; Department of Psychiatry and Psychotherapy, Psychiatry Neuroimaging Branch (PNB), University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Rauh J; Department of Psychiatry and Psychotherapy, Psychiatry Neuroimaging Branch (PNB), University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Steinmann S; Department of Psychiatry and Psychotherapy, Psychiatry Neuroimaging Branch (PNB), University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Mulert C; Department of Psychiatry and Psychotherapy, Psychiatry Neuroimaging Branch (PNB), University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Leicht G; Center of Psychiatry, Justus-Liebig University, 35392 Giessen, Germany.

Int J Mol Sci ; 24(3)2023 Jan 18.

Article em En | MEDLINE | ID: mdl-36768234

Assuntos

Ketamina; Esquizofrenia; Humanos; Masculino; Ketamina/farmacologia; Receptores de N-Metil-D-Aspartato/fisiologia; Esquizofrenia/tratamento farmacológico; Ácido Glutâmico; N-Metilaspartato; Eletroencefalografia; Biomarcadores

Palavras-chave

E/I balance; EEG; NMDAR; S-ketamine; glycine; Î³ oscillations

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esquizofrenia / Ketamina Tipo de estudo: Prognostic_studies Limite: Humans / Male Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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