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A discrete intermediate for the biosynthesis of both the enediyne core and the anthraquinone moiety of enediyne natural products.
Bhardwaj, Minakshi; Cui, Zheng; Daniel Hankore, Erome; Moonschi, Faruk H; Saghaeiannejad Esfahani, Hoda; Kalkreuter, Edward; Gui, Chun; Yang, Dong; Phillips, George N; Thorson, Jon S; Shen, Ben; Van Lanen, Steven G.
Afiliação
  • Bhardwaj M; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, KY 40536.
  • Cui Z; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, KY 40536.
  • Daniel Hankore E; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, KY 40536.
  • Moonschi FH; Department of Physiology, College of Medicine, University of Kentucky, Lexington, KY 40536.
  • Saghaeiannejad Esfahani H; Department of Microbiology, Immunology and Molecular Genetics, College of Medicine, University of Kentucky, Lexington, KY 40536.
  • Kalkreuter E; Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, University of Florida, Jupiter, FL 33458.
  • Gui C; Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, University of Florida, Jupiter, FL 33458.
  • Yang D; Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, University of Florida, Jupiter, FL 33458.
  • Phillips GN; Natural Products Discovery Center, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, University of Florida, Jupiter, FL 33458.
  • Thorson JS; Department of BioSciences, Rice University, Houston, TX 77005.
  • Shen B; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, KY 40536.
  • Van Lanen SG; Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, University of Florida, Jupiter, FL 33458.
Proc Natl Acad Sci U S A ; 120(9): e2220468120, 2023 02 28.
Article em En | MEDLINE | ID: mdl-36802426
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Produtos Biológicos / Escherichia coli Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Produtos Biológicos / Escherichia coli Idioma: En Ano de publicação: 2023 Tipo de documento: Article