Sex differences in the percentage of IRF5 positive B cells are associated with higher production of TNF-&#945; in women in response to TLR9 in humans.

Beisel, Claudia; Jordan-Paiz, Ana; Köllmann, Sandra; Ahrenstorf, Annika Elise; Padoan, Benedetta; Barkhausen, Tanja; Addo, Marylyn M; Altfeld, Marcus

Sex differences in the percentage of IRF5 positive B cells are associated with higher production of TNF-α in women in response to TLR9 in humans.

Beisel, Claudia; Jordan-Paiz, Ana; Köllmann, Sandra; Ahrenstorf, Annika Elise; Padoan, Benedetta; Barkhausen, Tanja; Addo, Marylyn M; Altfeld, Marcus.

Afiliação

Beisel C; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, 20251, Hamburg, Germany. claudia.beisel@med.uni-heidelberg.de.
Jordan-Paiz A; German Center for Infection Research (DZIF), University Medical Center Hamburg-Eppendorf, Lübeck-Borstel-Riems, Hamburg, Germany. claudia.beisel@med.uni-heidelberg.de.
Köllmann S; Research Department Virus Immunology, Leibniz Institute of Virology, 20251, Hamburg, Germany. claudia.beisel@med.uni-heidelberg.de.
Ahrenstorf AE; Department of Internal Medicine IV, Gastroenterology and Infectious Diseases, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany. claudia.beisel@med.uni-heidelberg.de.
Padoan B; Research Department Virus Immunology, Leibniz Institute of Virology, 20251, Hamburg, Germany.
Barkhausen T; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, 20251, Hamburg, Germany.
Addo MM; German Center for Infection Research (DZIF), University Medical Center Hamburg-Eppendorf, Lübeck-Borstel-Riems, Hamburg, Germany.
Altfeld M; Research Department Virus Immunology, Leibniz Institute of Virology, 20251, Hamburg, Germany.

Biol Sex Differ ; 14(1): 11, 2023 02 22.

Article em En | MEDLINE | ID: mdl-36814288

Assuntos

Linfócitos B; Fatores Reguladores de Interferon; Fator de Necrose Tumoral alfa; Feminino; Humanos; Masculino; Citocinas/metabolismo; Fatores Reguladores de Interferon/metabolismo; Caracteres Sexuais; Receptor 7 Toll-Like/metabolismo; Receptor Toll-Like 9/metabolismo; Fator de Necrose Tumoral alfa/metabolismo; Linfócitos B/metabolismo

Palavras-chave

B cells; Interferon regulatory factor 5; Sex differences; Toll-like receptor 7/9; Tumor necrosis factor-α

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos B / Fator de Necrose Tumoral alfa / Fatores Reguladores de Interferon Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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