A combined analysis of bulk and single-cell sequencing data reveals metabolic enzyme, pyruvate dehydrogenase E1 subunit beta (PDHB), as a prediction biomarker for the tumor immune response and immunotherapy.

Zhang, Fan; Yan, Yuanliang; Liang, Qiuju; Liu, Yuanhong; Wu, Geting; Xu, Zhijie; Yang, Keda

Zhang, Fan; Yan, Yuanliang; Liang, Qiuju; Liu, Yuanhong; Wu, Geting; Xu, Zhijie; Yang, Keda.

Afiliação

Zhang F; Department of Gynecology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Yan Y; Department of Physiology, School of Basic Medical Science, Central South University, Changsha, 410008, Hunan, China.
Liang Q; Department of Pharmacy, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Liu Y; Department of Pharmacy, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Wu G; Department of Pharmacy, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Xu Z; Department of Pathology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Yang K; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.

Heliyon ; 9(2): e13456, 2023 Feb.

Article em En | MEDLINE | ID: mdl-36816316

Palavras-chave

Immune checkpoint inhibitors; PDHB; Pan-cancer; Prognosis; Tumor infiltrating immune cells

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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