Clinical Utility of Genomic Tests Evaluating Homologous Recombination Repair Deficiency (HRD) for Treatment Decisions in Early and Metastatic Breast Cancer.

Galland, Loïck; Roussot, Nicolas; Desmoulins, Isabelle; Mayeur, Didier; Kaderbhai, Courèche; Ilie, Silvia; Hennequin, Audrey; Reda, Manon; Albuisson, Juliette; Arnould, Laurent; Boidot, Romain; Truntzer, Caroline; Ghiringhelli, François; Ladoire, Sylvain

Galland, Loïck; Roussot, Nicolas; Desmoulins, Isabelle; Mayeur, Didier; Kaderbhai, Courèche; Ilie, Silvia; Hennequin, Audrey; Reda, Manon; Albuisson, Juliette; Arnould, Laurent; Boidot, Romain; Truntzer, Caroline; Ghiringhelli, François; Ladoire, Sylvain.

Afiliação

Galland L; Department of Medical Oncology, Georges-François Leclerc Center, 21000 Dijon, France.
Roussot N; Platform of Transfer in Biological Oncology, Georges-François Leclerc Cancer Center, 21000 Dijon, France.
Desmoulins I; University of Burgundy-Franche Comté, 21000 Dijon, France.
Mayeur D; Department of Medical Oncology, Georges-François Leclerc Center, 21000 Dijon, France.
Kaderbhai C; Platform of Transfer in Biological Oncology, Georges-François Leclerc Cancer Center, 21000 Dijon, France.
Ilie S; University of Burgundy-Franche Comté, 21000 Dijon, France.
Hennequin A; Department of Medical Oncology, Georges-François Leclerc Center, 21000 Dijon, France.
Reda M; Department of Medical Oncology, Georges-François Leclerc Center, 21000 Dijon, France.
Albuisson J; Department of Medical Oncology, Georges-François Leclerc Center, 21000 Dijon, France.
Arnould L; Department of Medical Oncology, Georges-François Leclerc Center, 21000 Dijon, France.
Boidot R; Department of Medical Oncology, Georges-François Leclerc Center, 21000 Dijon, France.
Truntzer C; Department of Medical Oncology, Georges-François Leclerc Center, 21000 Dijon, France.
Ghiringhelli F; Department of Pathology and Tumor Biology, Georges-François Leclerc Center, 21000 Dijon, France.
Ladoire S; Research Center INSERM LNC-UMR1231, 21000 Dijon, France.

Cancers (Basel) ; 15(4)2023 Feb 18.

Article em En | MEDLINE | ID: mdl-36831640

Palavras-chave

BRCA; HRD score; NGS; PARPi; breast cancer; early breast cancer; homologous recombination deficiency; metastatic breast cancer; mutational signature; platinum salts

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article