A Proposed Methodology to Deal with the Impact of In Vitro Cellular Matrix on the Analytical Performances of a Targeted Metabolomic LC-HRMS Method.

Guitton, Jérôme; Gavotto, Floriane; Cros-Perrial, Emeline; Jordheim, Lars Petter; Machon, Christelle

Guitton, Jérôme; Gavotto, Floriane; Cros-Perrial, Emeline; Jordheim, Lars Petter; Machon, Christelle.

Afiliação

Guitton J; Biochemistry and Toxicology Laboratory, Lyon Sud Hospital, University Hospital of Lyon, CEDEX, 69495 Pierre-Bénite, France.
Gavotto F; Inserm U1052, CNRS UMR5286 Centre de Recherche en Cancérologie de Lyon, 69000 Lyon, France.
Cros-Perrial E; Toxicology Laboratory, Faculty of Pharmacy, University of Lyon, 69008 Lyon, France.
Jordheim LP; Biochemistry and Toxicology Laboratory, Lyon Sud Hospital, University Hospital of Lyon, CEDEX, 69495 Pierre-Bénite, France.
Machon C; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, L-4367 Belvaux, Luxembourg.

Int J Mol Sci ; 24(4)2023 Feb 13.

Article em En | MEDLINE | ID: mdl-36835182

Assuntos

Metaboloma; Metabolômica; Metabolômica/métodos; Linhagem Celular; Plasma; Técnicas de Cultura de Células

Palavras-chave

analytical performances; cell extracts; high resolution mass spectrometry; liquid chromatography; matrix effect; targeted metabolomic

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Metaboloma / Metabolômica Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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