In vitro and in vivo anti-inflammatory and anti-arthritic effect of Tinospora cordifolia via modulation of JAK/STAT pathway.

George, Genu; Shyni, G L; Mohan, Sreelekshmi; Abraham, Billu; Nisha, P; Ranjith, S; Rajankutty, K; Raghu, K G

George, Genu; Shyni, G L; Mohan, Sreelekshmi; Abraham, Billu; Nisha, P; Ranjith, S; Rajankutty, K; Raghu, K G.

Afiliação

George G; Biochemistry and Molecular Mechanism Laboratory, Agroprocessing and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram, Kerala, 695019, India.
Shyni GL; Biochemistry and Molecular Mechanism Laboratory, Agroprocessing and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram, Kerala, 695019, India.
Mohan S; Biochemistry and Molecular Mechanism Laboratory, Agroprocessing and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram, Kerala, 695019, India.
Abraham B; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.
Nisha P; Biochemistry and Molecular Mechanism Laboratory, Agroprocessing and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram, Kerala, 695019, India.
Ranjith S; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.
Rajankutty K; Biochemistry and Molecular Mechanism Laboratory, Agroprocessing and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram, Kerala, 695019, India.
Raghu KG; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.

Inflammopharmacology ; 31(2): 1009-1025, 2023 Apr.

Article em En | MEDLINE | ID: mdl-36840884

Assuntos

Artrite Experimental; Artrite Reumatoide; Tinospora; Humanos; Camundongos; Animais; Janus Quinases/metabolismo; Extratos Vegetais/farmacologia; Extratos Vegetais/uso terapêutico; Lipopolissacarídeos/farmacologia; Interleucina-6/metabolismo; Fator A de Crescimento do Endotélio Vascular/metabolismo; Fatores de Transcrição STAT/metabolismo; Transdução de Sinais; Anti-Inflamatórios/farmacologia; Anti-Inflamatórios/uso terapêutico; Citocinas/metabolismo; Artrite Reumatoide/tratamento farmacológico; Artrite Experimental/metabolismo; Fator de Necrose Tumoral alfa/metabolismo

Palavras-chave

Arthritis; JAK/STAT pathway; Tinospora cordifolia; VEGF

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Experimental / Artrite Reumatoide / Tinospora Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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