Nanoemulsion: A novel delivery approach for thermosensitive IgG on inhibiting milk fat oxidation.
Food Res Int
; 165: 112545, 2023 03.
Article
em En
| MEDLINE
| ID: mdl-36869456
ABSTRACT
IgG, a biologically active substance in bovine colostrum, is easily inactivated during heat treatment and edible process to lose its biological activity. Nanoemulsion can effectively protect IgG to maintain its biological activity from injurious treatment. In this study, a food-grade nanoemulsion system was developed to protect IgG from heat and acid damage. It can be found that the residual rate of nanoemulsion-protected IgG reaches 87.1â¯% after 10â¯min at 72⯰C. After 5â¯min at 82⯰C, the residual rate of IgG in nanoemulsion was 18.7â¯% higher than that in PBS. In the simulated gastric fluid at pH 2.0, the residual rate of IgG in the nanoemulsion reacted for 4â¯h was 21.5â¯% higher than that in PBS. It indicated that nanoemulsion system can improve the heat and acid resistance of IgG compared with others, which is attributed to the lowest water activity of nanoemulsion. The contents of hydroperoxide and malondialdehyde in the milk after storage for 72â¯h with nanoemulsion-protected IgG were 0.12â¯meq/kg and 0.04â¯mg/kg, respectively, less than that of PBS-protected IgG. IgG is protected by nanoemulsion can effectively protect its activity during processing, which provides a theoretical basis for its direct application in liquid milk.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Leite
/
Temperatura Alta
Limite:
Animals
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article