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Disruption of Phosphodiesterase 3A Binding to SERCA2 Increases SERCA2 Activity and Reduces Mortality in Mice With Chronic Heart Failure.
Skogestad, Jonas; Albert, Ingrid; Hougen, Karina; Lothe, Gustav B; Lunde, Marianne; Eken, Olav Søvik; Veras, Ioanni; Huynh, Ngoc Trang Thi; Børstad, Mira; Marshall, Serena; Shen, Xin; Louch, William E; Robinson, Emma Louise; Cleveland, Joseph C; Ambardekar, Amrut V; Schwisow, Jessica A; Jonas, Eric; Calejo, Ana I; Morth, Jens Preben; Taskén, Kjetil; Melleby, Arne Olav; Lunde, Per Kristian; Sjaastad, Ivar; Carlson, Cathrine Rein; Aronsen, Jan Magnus.
Afiliação
  • Skogestad J; Institute for Experimental Medical Research (J.S., I.A., K.H., M.L., O.S.E., I.V., M.B., S.M., X.S., W.E.L., P.K.L., I.S., C.R.C., J.M.A.), Oslo University Hospital and University of Oslo, Norway.
  • Albert I; Institute for Experimental Medical Research (J.S., I.A., K.H., M.L., O.S.E., I.V., M.B., S.M., X.S., W.E.L., P.K.L., I.S., C.R.C., J.M.A.), Oslo University Hospital and University of Oslo, Norway.
  • Hougen K; Institute for Experimental Medical Research (J.S., I.A., K.H., M.L., O.S.E., I.V., M.B., S.M., X.S., W.E.L., P.K.L., I.S., C.R.C., J.M.A.), Oslo University Hospital and University of Oslo, Norway.
  • Lothe GB; Department of Pharmacology, Oslo University Hospital, Norway (G.B.L.).
  • Lunde M; Bjørknes College, Oslo, Norway (G.B.L., J.M.A.).
  • Eken OS; Institute for Experimental Medical Research (J.S., I.A., K.H., M.L., O.S.E., I.V., M.B., S.M., X.S., W.E.L., P.K.L., I.S., C.R.C., J.M.A.), Oslo University Hospital and University of Oslo, Norway.
  • Veras I; Institute for Experimental Medical Research (J.S., I.A., K.H., M.L., O.S.E., I.V., M.B., S.M., X.S., W.E.L., P.K.L., I.S., C.R.C., J.M.A.), Oslo University Hospital and University of Oslo, Norway.
  • Huynh NTT; Department of Molecular Medicine, University of Oslo, Norway (O.S.E., I.V., N.T.T.-H., A.O.M., J.M.A.).
  • Børstad M; Institute for Experimental Medical Research (J.S., I.A., K.H., M.L., O.S.E., I.V., M.B., S.M., X.S., W.E.L., P.K.L., I.S., C.R.C., J.M.A.), Oslo University Hospital and University of Oslo, Norway.
  • Marshall S; Department of Molecular Medicine, University of Oslo, Norway (O.S.E., I.V., N.T.T.-H., A.O.M., J.M.A.).
  • Shen X; Department of Molecular Medicine, University of Oslo, Norway (O.S.E., I.V., N.T.T.-H., A.O.M., J.M.A.).
  • Louch WE; Institute for Experimental Medical Research (J.S., I.A., K.H., M.L., O.S.E., I.V., M.B., S.M., X.S., W.E.L., P.K.L., I.S., C.R.C., J.M.A.), Oslo University Hospital and University of Oslo, Norway.
  • Robinson EL; Institute for Experimental Medical Research (J.S., I.A., K.H., M.L., O.S.E., I.V., M.B., S.M., X.S., W.E.L., P.K.L., I.S., C.R.C., J.M.A.), Oslo University Hospital and University of Oslo, Norway.
  • Cleveland JC; Institute for Experimental Medical Research (J.S., I.A., K.H., M.L., O.S.E., I.V., M.B., S.M., X.S., W.E.L., P.K.L., I.S., C.R.C., J.M.A.), Oslo University Hospital and University of Oslo, Norway.
  • Ambardekar AV; Institute for Experimental Medical Research (J.S., I.A., K.H., M.L., O.S.E., I.V., M.B., S.M., X.S., W.E.L., P.K.L., I.S., C.R.C., J.M.A.), Oslo University Hospital and University of Oslo, Norway.
  • Schwisow JA; Division of Cardiology, Department of Medicine (E.L.R., A.V.A., J.A.S., E.J.), University of Colorado Anschutz Medical Campus, Aurora.
  • Jonas E; Department of Surgery (J.C.C.), University of Colorado Anschutz Medical Campus, Aurora.
  • Calejo AI; Division of Cardiology, Department of Medicine (E.L.R., A.V.A., J.A.S., E.J.), University of Colorado Anschutz Medical Campus, Aurora.
  • Morth JP; Division of Cardiology, Department of Medicine (E.L.R., A.V.A., J.A.S., E.J.), University of Colorado Anschutz Medical Campus, Aurora.
  • Taskén K; Division of Cardiology, Department of Medicine (E.L.R., A.V.A., J.A.S., E.J.), University of Colorado Anschutz Medical Campus, Aurora.
  • Melleby AO; Centre for Molecular Medicine Norway, Nordic European Molecular Biology Laboratory Partnership (A.I.C.C., J.P.M., K.T.), Oslo University Hospital and University of Oslo, Norway.
  • Lunde PK; Centre for Molecular Medicine Norway, Nordic European Molecular Biology Laboratory Partnership (A.I.C.C., J.P.M., K.T.), Oslo University Hospital and University of Oslo, Norway.
  • Sjaastad I; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby (J.P.M.).
  • Carlson CR; Centre for Molecular Medicine Norway, Nordic European Molecular Biology Laboratory Partnership (A.I.C.C., J.P.M., K.T.), Oslo University Hospital and University of Oslo, Norway.
  • Aronsen JM; Institute for Cancer Research, Oslo University Hospital and Institute for Clinical Medicine, University of Oslo, Norway (K.T.).
Circulation ; 147(16): 1221-1236, 2023 04 18.
Article em En | MEDLINE | ID: mdl-36876489
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: ATPases Transportadoras de Cálcio do Retículo Sarcoplasmático / Nucleotídeo Cíclico Fosfodiesterase do Tipo 3 / Insuficiência Cardíaca Tipo de estudo: Clinical_trials Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: ATPases Transportadoras de Cálcio do Retículo Sarcoplasmático / Nucleotídeo Cíclico Fosfodiesterase do Tipo 3 / Insuficiência Cardíaca Tipo de estudo: Clinical_trials Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article