Two-Step Validation Approach for Tools To Study the DNA Repair Enzyme SNM1A.

Fay, Ellen M; Newton, Ailish; Berney, Mark; El-Sagheer, Afaf H; Brown, Tom; McGouran, Joanna F

Fay, Ellen M; Newton, Ailish; Berney, Mark; El-Sagheer, Afaf H; Brown, Tom; McGouran, Joanna F.

Afiliação

Fay EM; School of Chemistry and Trinity Biomedical Sciences Institute, Trinity College Dublin, The University of Dublin, Dublin 2, D02 R590, Ireland.
Newton A; School of Chemistry and Trinity Biomedical Sciences Institute, Trinity College Dublin, The University of Dublin, Dublin 2, D02 R590, Ireland.
Berney M; School of Chemistry and Trinity Biomedical Sciences Institute, Trinity College Dublin, The University of Dublin, Dublin 2, D02 R590, Ireland.
El-Sagheer AH; Department of Chemistry, University of Oxford, Mansfield Road, OX1 3TA, Oxford, UK.
Brown T; Department of Chemistry, University of Oxford, Mansfield Road, OX1 3TA, Oxford, UK.
McGouran JF; School of Chemistry and Trinity Biomedical Sciences Institute, Trinity College Dublin, The University of Dublin, Dublin 2, D02 R590, Ireland.

Chembiochem ; 24(13): e202200756, 2023 07 03.

Article em En | MEDLINE | ID: mdl-36917742

Assuntos

Proteínas de Ciclo Celular; Exodesoxirribonucleases; Exodesoxirribonucleases/metabolismo; Enzimas Reparadoras do DNA/química; Enzimas Reparadoras do DNA/metabolismo; Reparo do DNA; Oligonucleotídeos/química

Palavras-chave

DNA repair; SNM1A; fragment-based screening; metal-binding groups; oligonucleotide modification

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Ciclo Celular / Exodesoxirribonucleases Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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