Evidence for solanidine as a dietary CYP2D6 biomarker: Significant correlation with risperidone metabolism.

Wollmann, Birgit M; Smith, Robert L; Kringen, Marianne Kristiansen; Ingelman-Sundberg, Magnus; Molden, Espen; Størset, Elisabet

Wollmann, Birgit M; Smith, Robert L; Kringen, Marianne Kristiansen; Ingelman-Sundberg, Magnus; Molden, Espen; Størset, Elisabet.

Afiliação

Wollmann BM; Center for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway.
Smith RL; Center for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway.
Kringen MK; NORMENT, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Ingelman-Sundberg M; Center for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway.
Molden E; Department of Life Science and Health, OsloMet - Oslo Metropolitan University, Oslo, Norway.
Størset E; Department of Physiology and Pharmacology, Section of Pharmacogenetics, Karolinska Institutet, Stockholm, Sweden.

Br J Clin Pharmacol ; 90(3): 740-747, 2024 03.

Article em En | MEDLINE | ID: mdl-36960588

Assuntos

Citocromo P-450 CYP2D6; Diosgenina; Risperidona; Humanos; Biomarcadores; Citocromo P-450 CYP2D6/genética; Citocromo P-450 CYP2D6/metabolismo; Palmitato de Paliperidona; Risperidona/administração & dosagem; Risperidona/metabolismo

Palavras-chave

CYP2D6; phenotyping; precision medicine; solanidine biomarker

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Risperidona / Citocromo P-450 CYP2D6 / Diosgenina Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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