Cyclopamine targeting hedgehog modulates nuclear control of the osteoblast activity.

da Costa Fernandes, Célio J; Ferreira, Marcel Rodrigues; Zambuzzi, Willian Fernando

da Costa Fernandes, Célio J; Ferreira, Marcel Rodrigues; Zambuzzi, Willian Fernando.

Afiliação

da Costa Fernandes CJ; Departament of Chemistry and Biochemistry, São Paulo State University (UNESP), Institute of Biosciences, Campus Botucatu, São Paulo ZipCode 18618-970, Brazil.
Ferreira MR; Departament of Chemistry and Biochemistry, São Paulo State University (UNESP), Institute of Biosciences, Campus Botucatu, São Paulo ZipCode 18618-970, Brazil.
Zambuzzi WF; Departament of Chemistry and Biochemistry, São Paulo State University (UNESP), Institute of Biosciences, Campus Botucatu, São Paulo ZipCode 18618-970, Brazil. Electronic address: w.zambuzzi@unesp.br.

Cells Dev ; 174: 203836, 2023 06.

Article em En | MEDLINE | ID: mdl-36972848

Assuntos

Ouriços; Inflamassomos; Animais; Inflamassomos/farmacologia; Osteogênese/genética; Osteoblastos/fisiologia

Palavras-chave

ASC; Anti-inflammatory; Cyclopamine; Inflammasome; Inflammation; Osteoblast; Sonic Hedgehog; TGFß; TNFα

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inflamassomos / Ouriços Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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