Novel Generation of FAP Inhibitor-Based Homodimers for Improved Application in Radiotheranostics.

Martin, Marcel; Ballal, Sanjana; Yadav, Madhav Prasad; Bal, Chandrasekhar; Van Rymenant, Yentl; De Loose, Joni; Verhulst, Emile; De Meester, Ingrid; Van Der Veken, Pieter; Roesch, Frank

Martin, Marcel; Ballal, Sanjana; Yadav, Madhav Prasad; Bal, Chandrasekhar; Van Rymenant, Yentl; De Loose, Joni; Verhulst, Emile; De Meester, Ingrid; Van Der Veken, Pieter; Roesch, Frank.

Afiliação

Martin M; Department of Chemistry-TRIGA Site, Johannes Gutenberg University Mainz, 55128 Mainz, Germany.
Ballal S; Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi 110029, India.
Yadav MP; Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi 110029, India.
Bal C; Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi 110029, India.
Van Rymenant Y; Laboratory of Medical Biochemistry, Department of Pharmaceutical Sciences, University of Antwerp, 2610 Wilrijk, Belgium.
De Loose J; Laboratory of Medical Biochemistry, Department of Pharmaceutical Sciences, University of Antwerp, 2610 Wilrijk, Belgium.
Verhulst E; Laboratory of Medical Biochemistry, Department of Pharmaceutical Sciences, University of Antwerp, 2610 Wilrijk, Belgium.
De Meester I; Laboratory of Medical Biochemistry, Department of Pharmaceutical Sciences, University of Antwerp, 2610 Wilrijk, Belgium.
Van Der Veken P; Laboratory of Medicinal Chemistry, Department of Pharmaceutical Sciences, University of Antwerp, 2610 Wilrijk, Belgium.
Roesch F; Department of Chemistry-TRIGA Site, Johannes Gutenberg University Mainz, 55128 Mainz, Germany.

Cancers (Basel) ; 15(6)2023 Mar 21.

Article em En | MEDLINE | ID: mdl-36980775

Palavras-chave

FAPi dimers; fibroblast activation protein alpha (FAP); homodimeric FAPi-based radiopharmaceuticals; medullary thyroid cancer; positron emission tomography (PET); radioligand therapy (RLT); radiometals; radionuclide therapy (RNT); targeted alpha-particle therapy (TAT); theranostics

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article