Natural Product Skatole Ameliorates Lipotoxicity-Induced Multiple Hepatic Damage under Hyperlipidemic Conditions in Hepatocytes.

Hong, Sin-Hyoung; Hong, Yeonhee; Lee, Minji; Keum, Byeong-Rak; Kim, Gun-Hwa

Hong, Sin-Hyoung; Hong, Yeonhee; Lee, Minji; Keum, Byeong-Rak; Kim, Gun-Hwa.

Afiliação

Hong SH; Division of Research Center for Bioconvergence Analysis, Korea Basic Science Institute, Cheongju 28119, Republic of Korea.
Hong Y; Department of Bio-Analytical Science, University of Science and Technology, Daejeon 34113, Republic of Korea.
Lee M; Division of Research Center for Bioconvergence Analysis, Korea Basic Science Institute, Cheongju 28119, Republic of Korea.
Keum BR; Division of Research Center for Bioconvergence Analysis, Korea Basic Science Institute, Cheongju 28119, Republic of Korea.
Kim GH; Department of Bio-Analytical Science, University of Science and Technology, Daejeon 34113, Republic of Korea.

Nutrients ; 15(6)2023 Mar 20.

Article em En | MEDLINE | ID: mdl-36986221

Assuntos

Hepatopatia Gordurosa não Alcoólica; Humanos; Hepatopatia Gordurosa não Alcoólica/metabolismo; Escatol/efeitos adversos; Escatol/metabolismo; Ácidos Graxos não Esterificados/metabolismo; Hepatócitos; Fígado/metabolismo; Ácidos Graxos/metabolismo; Estresse do Retículo Endoplasmático

Palavras-chave

endoplasmic reticulum stress; hepatic damage; lipid accumulation; lipoapoptosis; lipotoxicity; natural products; nonalcoholic fatty liver disease; oxidative stress; skatole

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatopatia Gordurosa não Alcoólica Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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