Ex-vivo dose response characterization of the recently identified <i>EDA2R</i> gene after low level radiation exposures and comparison with <i>FDXR</i> gene expression and the Î³H2AX focus assay.

Schüle, Simone; Hackenbroch, Carsten; Beer, Meinrad; Muhtadi, Razan; Hermann, Cornelius; Stewart, Samantha; Schwanke, Daniel; Ostheim, Patrick; Port, Matthias; Scherthan, Harry; Abend, Michael

Ex-vivo dose response characterization of the recently identified EDA2R gene after low level radiation exposures and comparison with FDXR gene expression and the Î³H2AX focus assay.

Schüle, Simone; Hackenbroch, Carsten; Beer, Meinrad; Muhtadi, Razan; Hermann, Cornelius; Stewart, Samantha; Schwanke, Daniel; Ostheim, Patrick; Port, Matthias; Scherthan, Harry; Abend, Michael.

Afiliação

Schüle S; Bundeswehr Institute of Radiobiology, Affiliated to the University of Ulm, Munich, Germany.
Hackenbroch C; Department of Diagnostic and Interventional Radiology and Neuroradiology, German Armed Force Hospital of Ulm, Ulm, Germany.
Beer M; Department of Radiology, University Hospital of Ulm, Ulm, Germany.
Muhtadi R; Department of Radiology, University Hospital of Ulm, Ulm, Germany.
Hermann C; Bundeswehr Institute of Radiobiology, Affiliated to the University of Ulm, Munich, Germany.
Stewart S; Bundeswehr Institute of Radiobiology, Affiliated to the University of Ulm, Munich, Germany.
Schwanke D; Bundeswehr Institute of Radiobiology, Affiliated to the University of Ulm, Munich, Germany.
Ostheim P; Bundeswehr Institute of Radiobiology, Affiliated to the University of Ulm, Munich, Germany.
Port M; Bundeswehr Institute of Radiobiology, Affiliated to the University of Ulm, Munich, Germany.
Scherthan H; Bundeswehr Institute of Radiobiology, Affiliated to the University of Ulm, Munich, Germany.
Abend M; Bundeswehr Institute of Radiobiology, Affiliated to the University of Ulm, Munich, Germany.

Int J Radiat Biol ; 99(10): 1584-1594, 2023.

Article em En | MEDLINE | ID: mdl-36988552

Assuntos

Bioensaio; Exposição à Radiação; Animais; Humanos; Relação Dose-Resposta à Radiação; Bioensaio/métodos; Exposição à Radiação/efeitos adversos; Expressão Gênica

Palavras-chave

EDA2R; FDXR; biomarker; low-level radiation exposure; qRT-PCR; Î³-H2AX DSB foci

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bioensaio / Exposição à Radiação Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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