Targeted DNA integration in human cells without double-strand breaks using CRISPR RNA-guided transposases.

Lampe, George D; King, Rebeca T; Halpin-Healy, Tyler S; Klompe, Sanne E; Hogan, Marcus I; Vo, Phuc Leo H; Tang, Stephen; Chavez, Alejandro; Sternberg, Samuel H

Lampe, George D; King, Rebeca T; Halpin-Healy, Tyler S; Klompe, Sanne E; Hogan, Marcus I; Vo, Phuc Leo H; Tang, Stephen; Chavez, Alejandro; Sternberg, Samuel H.

Afiliação

Lampe GD; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.
King RT; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.
Halpin-Healy TS; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.
Klompe SE; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.
Hogan MI; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.
Vo PLH; Department of Molecular Pharmacology and Therapeutics, Columbia University, New York, NY, USA.
Tang S; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.
Chavez A; Department of Pathology and Cell Biology, Columbia University, New York, NY, USA.
Sternberg SH; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.

bioRxiv ; 2023 Mar 18.

Article em En | MEDLINE | ID: mdl-36993517

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article