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Persistent mTORC1 activation due to loss of liver tuberous sclerosis complex 1 promotes liver injury in alcoholic hepatitis.
Chao, Xiaojuan; Wang, Shaogui; Ma, Xiaowen; Zhang, Chen; Qian, Hui; Williams, Sha Neisha; Sun, Zhaoli; Peng, Zheyun; Liu, Wanqing; Li, Feng; Sheshadri, Namratha; Zong, Wei-Xing; Ni, Hong-Min; Ding, Wen-Xing.
Afiliação
  • Chao X; Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, Kansas, USA.
  • Wang S; Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, Kansas, USA.
  • Ma X; Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, Kansas, USA.
  • Zhang C; Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, Kansas, USA.
  • Qian H; Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, Kansas, USA.
  • Williams SN; Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, Kansas, USA.
  • Sun Z; Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Peng Z; Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Detroit, Michigan.
  • Liu W; Department of Pharmacology, School of Medicine, Wayne State University, Detroit, Michigan, USA.
  • Li F; Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Detroit, Michigan.
  • Sheshadri N; Department of Pharmacology, School of Medicine, Wayne State University, Detroit, Michigan, USA.
  • Zong WX; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, USA.
  • Ni HM; Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, New Jersey, USA.
  • Ding WX; Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, New Jersey, USA.
Hepatology ; 78(2): 503-517, 2023 08 01.
Article em En | MEDLINE | ID: mdl-36999531
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Alvo Mecanístico do Complexo 1 de Rapamicina / Proteína 1 do Complexo Esclerose Tuberosa / Hepatite Alcoólica / Hepatopatias Alcoólicas Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Alvo Mecanístico do Complexo 1 de Rapamicina / Proteína 1 do Complexo Esclerose Tuberosa / Hepatite Alcoólica / Hepatopatias Alcoólicas Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article