Exploring the Effects of Chirality of 5-methyl-5-[4-(4-oxo-3H-quinazolin-2-yl) phenyl]imidazolidine-2,4-dione and its Derivatives on the Oncological Target Tankyrase 2. Atomistic Insights.

Quintina Peters, Xylia; Poonan, Preantha; Salifu Yakubu, Elliasu; Issa Alahmdi, Mohamed; Abo-Dya, Nader E; Soliman, Mahmoud

Quintina Peters, Xylia; Poonan, Preantha; Salifu Yakubu, Elliasu; Issa Alahmdi, Mohamed; Abo-Dya, Nader E; Soliman, Mahmoud.

Afiliação

Quintina Peters X; University of KwaZulu-Natal Pharmaceutical Sciences Durban South Africa.
Poonan P; University of KwaZulu-Natal Molecular Bio-Computation & Drug Design Durban South Africa.
Salifu Yakubu E; University of KwaZulu-Natal Pharmaceutical Chemistry Durban South Africa.
Issa Alahmdi M; University of Tabuk Department of Chemistry Tabuk Saudi Arabia.
Abo-Dya NE; University of Tabuk Department of Pharmaceutical Chemistry Tabuk Saudi Arabia.
Soliman M; University of KwaZulu-Natal Pharmaceutical Sciences Durban South Africa.

Curr Pharm Biotechnol ; 2023 Mar 30.

Article em En | MEDLINE | ID: mdl-37005548

Palavras-chave

chirality; computer-aided drug design; molecular dynamic simulation; racemic mixture; tankyrase

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article