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Obesity defined molecular endotypes in the synovium of patients with osteoarthritis provides a rationale for therapeutic targeting of fibroblast subsets.
Wijesinghe, Susanne N; Badoume, Amel; Nanus, Dominika E; Sharma-Oates, Archana; Farah, Hussein; Certo, Michelangelo; Alnajjar, Fawzeyah; Davis, Edward T; Mauro, Claudio; Lindsay, Mark A; Jones, Simon W.
Afiliação
  • Wijesinghe SN; Institute of Inflammation and Ageing, MRC-ARUK Centre for Musculoskeletal Ageing Research, University of Birmingham, Birmingham, UK.
  • Badoume A; Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath, UK.
  • Nanus DE; Institute of Inflammation and Ageing, MRC-ARUK Centre for Musculoskeletal Ageing Research, University of Birmingham, Birmingham, UK.
  • Sharma-Oates A; School of Biosciences, University of Birmingham, Birmingham, UK.
  • Farah H; Institute of Inflammation and Ageing, MRC-ARUK Centre for Musculoskeletal Ageing Research, University of Birmingham, Birmingham, UK.
  • Certo M; Institute of Inflammation and Ageing, MRC-ARUK Centre for Musculoskeletal Ageing Research, University of Birmingham, Birmingham, UK.
  • Alnajjar F; Institute of Inflammation and Ageing, MRC-ARUK Centre for Musculoskeletal Ageing Research, University of Birmingham, Birmingham, UK.
  • Davis ET; The Royal Orthopaedic Hospital, Birmingham, UK.
  • Mauro C; Institute of Inflammation and Ageing, MRC-ARUK Centre for Musculoskeletal Ageing Research, University of Birmingham, Birmingham, UK.
  • Lindsay MA; Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath, UK.
  • Jones SW; Institute of Inflammation and Ageing, MRC-ARUK Centre for Musculoskeletal Ageing Research, University of Birmingham, Birmingham, UK.
Clin Transl Med ; 13(4): e1232, 2023 04.
Article em En | MEDLINE | ID: mdl-37006170

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite / Proteômica Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite / Proteômica Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article