MiR-10b-5p Impairs TET2-Mediated Inhibition of PD-L1 Transcription Thus Promoting Immune Evasion and Tumor Progression in Glioblastoma.

Du, Wei; Chen, Dayu; Wei, Ke; Yu, Duo; Gan, Zhiqiang; Xu, Guozheng; Yao, Guojie

Du, Wei; Chen, Dayu; Wei, Ke; Yu, Duo; Gan, Zhiqiang; Xu, Guozheng; Yao, Guojie.

Afiliação

Du W; Department of Neurosurgery, General Hospital of Central Theater Command.
Chen D; Department of Neurosurgery, General Hospital of Central Theater Command.
Wei K; Department of Neurosurgery, General Hospital of Central Theater Command.
Yu D; Department of Neurosurgery, General Hospital of Central Theater Command.
Gan Z; Department of Neurosurgery, General Hospital of Central Theater Command.
Xu G; Department of Neurosurgery, General Hospital of Central Theater Command.
Yao G; Department of Neurosurgery, General Hospital of Central Theater Command.

Tohoku J Exp Med ; 260(3): 205-214, 2023 Jul 08.

Article em En | MEDLINE | ID: mdl-37019647

Assuntos

Dioxigenases; Glioblastoma; MicroRNAs; Humanos; Antígeno B7-H1/genética; Antígeno B7-H1/metabolismo; Linhagem Celular Tumoral; Proliferação de Células; Dioxigenases/genética; Dioxigenases/metabolismo; Proteínas de Ligação a DNA/genética; Proteínas de Ligação a DNA/metabolismo; Regulação Neoplásica da Expressão Gênica; Glioblastoma/genética; Glioblastoma/metabolismo; Glioblastoma/patologia; Evasão da Resposta Imune; MicroRNAs/genética; MicroRNAs/metabolismo

Palavras-chave

PD-L1; TET2; glioblastoma; immune evasion; miR-10b-5p

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glioblastoma / MicroRNAs / Dioxigenases Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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