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Improving the sensitivity of in vivo CRISPR off-target detection with DISCOVER-Seq.
Zou, Roger S; Liu, Yang; Gaido, Oscar E Reyes; Konig, Maximilian F; Mog, Brian J; Shen, Leo L; Aviles-Vazquez, Franklin; Marin-Gonzalez, Alberto; Ha, Taekjip.
Afiliação
  • Zou RS; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Liu Y; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Gaido OER; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Konig MF; Department of Biophysics, Johns Hopkins University, Baltimore, MD, USA.
  • Mog BJ; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Shen LL; Division of Rheumatology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Aviles-Vazquez F; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Marin-Gonzalez A; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Ha T; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Nat Methods ; 20(5): 706-713, 2023 05.
Article em En | MEDLINE | ID: mdl-37024653
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistemas CRISPR-Cas / Pró-Proteína Convertase 9 Tipo de estudo: Diagnostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistemas CRISPR-Cas / Pró-Proteína Convertase 9 Tipo de estudo: Diagnostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article