Dual action anti-inflammatory/antiviral isoquinoline alkaloids as potent naturally occurring anti-SARS-CoV-2 agents: A combined pharmacological and medicinal chemistry perspective.

Valipour, Mehdi; Hosseini, Asieh; Di Sotto, Antonella; Irannejad, Hamid

Valipour, Mehdi; Hosseini, Asieh; Di Sotto, Antonella; Irannejad, Hamid.

Afiliação

Valipour M; Razi Drug Research Center, Iran University of Medical Sciences, Tehran, Iran.
Hosseini A; Razi Drug Research Center, Iran University of Medical Sciences, Tehran, Iran.
Di Sotto A; Department of Physiology and Pharmacology "V. Erspamer", Sapienza University of Rome, Rome, Italy.
Irannejad H; Department of Medicinal Chemistry, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.

Phytother Res ; 37(5): 2168-2186, 2023 May.

Article em En | MEDLINE | ID: mdl-37039761

Assuntos

Alcaloides; COVID-19; Humanos; Química Farmacêutica; SARS-CoV-2; Pandemias; Isoquinolinas/farmacologia; Isoquinolinas/uso terapêutico; Alcaloides/farmacologia; Alcaloides/uso terapêutico; Anti-Inflamatórios/farmacologia; Anti-Inflamatórios/uso terapêutico; Antivirais/farmacologia; Antivirais/uso terapêutico

Palavras-chave

COVID-19; Papaverine; anti-inflammatory; emetine; isoquinoline-based alkaloids; p38 MAPK pathway

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Alcaloides / COVID-19 Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google